肝移植術圍手術期脾亢的處理

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肝移植術圍手術期脾亢的處理
作者:蔣安,呂毅,劉昌,李宗芳,李泉源,史源,馬鋒

【關鍵詞】 肝移植;脾功能亢進;移植物排斥;血小板;肺部感染
  Treatment of hypersplenism in perioperation of liver transplantation
  【Abstract】AIM: To observe the changes in hypersplenism after orthoto METHODS: Splenectomy or splenic artery ligation was performed on 15(group A) of the consecutive 115 patients undergoing OLT in 5 years, before OTC in 11 of them and during OTC in 4 of them. Sixtyeight randomly selected agematched patients undergoing OTC within the same period but without splenectomy or splenic artery ligation were used as controls (group B). Acute rejection rate , blood PLT count, incidence of lung infection and PVF/HAF(portal venous flow/ hepatic arterial flow) were calculated and analyzed. RESULTS: Lung infaction rate of group A was 85%, significantly higher than that of group B (54%, P